姐姐伦理电影

    1. <form id=fZWczxbmO><nobr id=fZWczxbmO></nobr></form>
      <address id=fZWczxbmO><nobr id=fZWczxbmO><nobr id=fZWczxbmO></nobr></nobr></address>

      slogan

      VectorBuilder最新發表文章

      miniVec: A miniaturized plasmid backbone supporting antibiotic-free and additive-free fermentation with enhanced yield and functionality

      Silk J. Shi, et al. bioRxiv. 2025 (DOI: https://doi.org/10.1101/2025.10.02.679775)

      概述:miniVec是一種有著微型化骨架的新型質粒系統,其與傳統質粒相比具備卓越的效力、安全性和可生産性。具體而言,miniVec在多種體外和體內應用中(如瞬時轉染、病毒包裝、轉座子及CRISPR介導的基因組整合、裸DNA疫苗等)不僅能顯著提升質粒産量和功能表現,還完全不具備免疫原性或毒性。因此,miniVec系統代表了下一代質粒平台,其既能降低生産成本,又能提高基因治療應用的有效性與安全性。

      查看全文 >>
      查看新闻稿 >>

      VectorBuilder平台是云舟生物独创的 “一站式” 智能載體设计平台,颠覆性地变革实验室DIY載體效率低下的传统方式,将科研人员从实验室DIY載體的繁复工作中解放出来,支持其自主在线设计和订购个性化載體。  了解更多

      雲舟生物作爲引領全球基因遞送技術的創新型企業,致力于系統性攻克基因遞送行業的關鍵技術瓶頸,我們的動態一直備受各界關注。

      Alexander Atkin

      Alexander Atkin


      University of Cambridge, UK
      I was really happy with VectorBuilder's services for my PhD project, I had approached other companies to synthesise DNA containing my gene of interest, but none of them could manage thanks to some repetitive elements, even with codon optimising. Not only were VectorBuilder able to clone it perfectly but no codon optimising was required! I was also able to design and purchase lentiviruses for expressing said gene very easily and with a pretty quick turnaround of just a few weeks total, thanks to the efforts of my local VectorBuilder representative. I would highly recommend VectorBuilder for any lentivirus/gene synthesis projects and will be using them in the future if required too.
      Dr. Pedro Fonseca

      Dr. Pedro Fonseca


      Karolinska Institutet, Sweden
      We have been using VectorBuilder to design and produce different kinds of lentiviral and adenoviral constructs to be used on cancer research over the years. I particularly appreciate your customer support where you can get expert help with designing custom vectors tailored to your research questions. I also like the modular aspect where we can choose to order DNA, bacterial stocks and/or ready-made viral titers; coupled with the nice user interface and vector maps in your website, it makes it so much easier not only to keep track of all the constructs, but to also share them with other researchers that want to use and order those same constructs. Thank you for your services, you have helped our research projects immensely!

      孫彩軍教授


      中山大學
      与云舟生物的合作相当棒!mRNA作为当今的热门疫苗技术,大量被用于多种传染性和非传染性疾病的预防和治疗。云舟生物的Daniel Meng研发团队为我快速搭建了一个IVT mRNA CRO平台,通过与他们的紧密合作我们共同开发了针对HIV和流感的mRNA疫苗。他们的科学专业性与问题解决能力让我印象深刻。云舟生物再一次向我证明他们是值得信赖的合作伙伴。

      James Cox


      Wolfson Inst for Biomedical Research, UK
      For several years we have used VectorBuilder for generating expression constructs and custom AAVs. Designing constructs is easy – either use the website or send a request of what you want by email - detailed construct designs are usually in your inbox within 24 hrs. Prices, turnaround times and quality of product mean that ordering from VectorBuilder is just the obvious decision to make when planning experiments. I recommend their services to all my friends.

      Dr. Bogang Wu


      Harvard Medical School, USA
      VectorBuilder has been instrumental in supporting my research by providing timely and reliable vector cloning and virus packaging services. Joaquin is always responsive to my requests and vector design needs, efficiently addressing them with care and attention to detail. His dedication to the success of my projects has contributed to several publications. I highly recommend their services.
      Dr. Leesa Sampson

      Dr. Leesa Sampson


      Vanderbilt Genome Editing Resource, USA
      VectorBuilder’s plasmid and virus preparation services are reliable, competitively priced, and exceptional at handling challenging constructs. Their customer service is top-notch, making them an essential part of our workflow.

      Alexander Goginashvili


      University of California San Diego, USA
      We have successfully generated several vectors with VectorBuilder and very much hope there will be many more to come. Their website is very easy to navigate. Timing is really appealing and the prices are convenient. Special thanks to Shelley Wu, the service rep in San Diego. She is extremely helpful and approachable. Overall, VectorBuilder is a huge help!

      Julius Bogomolovas


      UCSD School of Medicine, USA
      The straightforward, intuitive interface allowed me to design my construct, by a simply copying-and-pasting sequence of my gene and choosing the right promoter and reporter from an impressive scroll down menu. The vector and recombinant viruses were made on time at a very competitive price with no extra cost for aliquoting into working aliquots. I highly recommend VectorBuilder for a complete recombinant virus production pipeline.

      Evgenia Salta


      Katholieke Universiteit Leuven/VIB, Belgium
      VectorBuilder has been the partner every researcher would wish for during those dark moments of paper revision. They offer the complete package: a wide range of viral vector design options, an extremely user-friendly and intuitive website, direct communication, personal and knowledgeable step-by-step guidance throughout the designing and ordering process, accountability, amazing discounts, unique customer support, fast shipping, and guaranteed virus titers and efficiency. So here’s my big thumbs up for a great product and service provider who has proven indispensable in addressing my research questions!

      Frank Borriello


      Alloplex Biotherapeutics, USA
      VectorBuilder has provided incredible value and customer service throughout the entire process from product selection, custom design assistance, order submission, status reports and ultimate delivery management. The custom products I purchased from them performed exactly as advertised and in fact surpassed my expectations. I would recommend VectorBuilder to anyone requiring this type of product.
      Dr. Cristina Martinez Gonzalez

      Dr. Cristina Martinez Gonzalez


      University of Edinburgh, United Kingdom
      VectorBuilder's AAV serotype panel helped us to choose the best expressing serotype for our brain area and animal model of interest. By piloting injections using a selection of serotypes provided in the panel, we obtained invaluable pilot data before ordering a large scale virus production. This allowed us to save a considerable amount of time and resources. The technical support was great, they answer our questions promptly provided great advice. VectorBuilder technical support team further help us designing and cloning our AAV viral vector. Our preliminary data allowed to map retrogradely labelled neurons in the amygdala using light-sheet microscopy. We would not hesitate to use VectorBuilder for our next projects.
      Constantine Tzouanas

      Constantine Tzouanas


      Massachusetts Institute of Technology, USA
      VectorBuilder was fantastically helpful for our AAV experiments - wonderful for talking through our goals and proposed order, and very responsive in keeping us up-to-date on our order's progress. The AAV worked very well, and working with VectorBuilder (and especially Maria Pascual) was a very positive experience!

      Xueqing Xia


      UT MD Anderson Cancer Center, USA
      We are testing different vectors for T cell therapy, and VectorBuilder provides a one stop solution for design, construct and manufacturing numerus lentiviral vectors for us. One of our vector was GMP manufactured by VectorBuilder and move to FDA approved clinical trial. We had great experience working with VectorBuilder, from communication to product QC, high level of service.
      Dr. Garron Dodd

      Dr. Garron Dodd


      The University of Melbourne, Australia
      VectorBuilder is truly exceptional, offering best-in-class services for viral vector generation. Their contributions are so integral to our research that I consider them an invaluable extension of our lab.

      Dr. Shaikh Nisar Ali


      Long Island University, USA
      We utilized two lentiviral vectors, lenti-CYP and lenti-Ctr, from VectorBuilder Inc. in our study on Lgr5+ intestinal stem cells. The lenti-CYP vector, encoding the hCYP27B1 gene, enabled de novo synthesis of locally high 1,25(OH)2D concentrations, proving crucial for our investigation. The high-quality design, including promoter specificity and integrated resistance genes, ensured reliable gene expression and successful transduction. The control vector, lenti-Ctr, further allowed precise experimental comparisons. VectorBuilder's products significantly contributed to the success of our research, and I highly recommend their custom vector services for advanced molecular biology applications.
      Dr. George-Lucian Moldovan

      Dr. George-Lucian Moldovan


      The Pennsylvania State University, USA
      We were working on nascent DNA processing at stalled replication forks in BRCA-deficient cells and used a lentiviral construct and CRISPR/Cas9-mediated genome editing from VectorBuilder to create our knockout cell lines. The VectorBuilder support team have great technical expertise, are very supportive and fantastic to work with. I highly recommend VectorBuilder's services to accelerate research projects.
      • Direct conversion of urine-derived cells into functional motor neuron-like cells by defined transcription factors

        Products & Services: vector cloning, lentivirus, adenovirus
        Nature. 2024. doi: 10.1038/s41598-024-73759-0. IF:50.5
      • Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

        Cancer Cell. 2023. doi: 10.1016/j.ccell.2022.12.003. IF: 50.3
      • Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health

        Products & Services: vector cloning, AAV8
        Nat Metab. 2024. doi: 10.1038/s42255-024-01126-4. IF: 18.9
      • Lactylated Apolipoprotein C‐II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis

        Products & Services: vector cloning, MMLV
        Adv Sci. 2024. doi: 10.1002/advs.202406333. IF: 14.3
      • A novel ACE2 decoy for both neutralization of SARS-CoV-2 variants and killing of infected cells

        Products & Services: stable cell line, S protein-pseudotyped lentivirus
        Front Immunol. 2023. doi: 10.3389/fimmu.2023.1204543. IF: 7.3
      • Phase Separation Enhanced PROTAC for Highly Efficient Protein Degradation

        Products & Services:  IVT RNA and LNP manufacturing
        Biomacromolecules. 2024. doi: 10.1021/acs.biomac.4c00424. IF: 5.5
      • MMP12 disrupts epithelial barrier integrity in oral lichen planus by degrading fibronectin

        Products & Services: vector cloning
        Nature. 2024. doi: 10.1038/s41598-024-78930-1. IF: 50.5
      • The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution

        Products & Services: vector cloning
        Nature. 2024. doi: 10.1038/s41586-024-07955-3. IF: 50.5
      • Acid-exposed and hypoxic cancer cells do not overlap but are interdependent for unsaturated fatty acid resources

        Products & Services: vector cloning
        Nature. 2024. doi: 10.1038/s41467-024-54435-3. IF: 50.5
      • Mammalian ubiquitous promoter isolated from proximal regulatory region of bovine MSTN gene

        Products & Services: vector cloning, lentivirus
        Nature. 2024. doi: 10.1038/s41598-024-76937-2. IF: 50.5
      • Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia

        Products & Services: vector cloning, lentivirus
        Nature. 2024. doi: 10.1038/s41467-024-54108-1. IF: 50.5
      • Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

        Products & Services: vector cloning
        Cancer cell. 2024. doi: 10.1016/j.ccell.2024.08.018. IF: 48.8
      • Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

        Products & Services: vector cloning, lentivirus
        Cancer Cell. 2024. doi: 10.1016/j.ccell.2024.10.010. IF: 48.8
      • TULIPs decorate the three-dimensional genome of PFA ependymoma

        Products & Services: vector cloning
        Cell. 2024. doi: 10.1016/j.cell.2024.06.023. IF: 45.5
      • A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification

        Products & Services: vector cloning
        Cell. 2024. doi: 10.1016/j.cell.2024.09.026. IF: 45.5
      • snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification

        Products & Services: vector cloning
        Cell. 2025. doi: 10.1016/j.cell.2024.10.046. IF: 45.5
      • MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids

        Products & Services: vector cloning
        Cell Host Microbe. 2024. doi: 10.1016/j.chom.2024.09.002. IF: 20.6
      • Discovery and engineering of ChCas12b for precise genome editing

        Products & Services: AAV9
        Sci. Bull. 2024. doi: 10.1016/j.scib.2024.06.012. IF: 18.8
      • An atlas of the aging mouse proteome reveals the features of age-related post-transcriptional dysregulation

        Products & Services: vector cloning
        Nat Commun. 2024. doi: 10.1038/s41467-024-52845-x. IF: 14.7
      • Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy

        Products & Services: vector cloning, MSCV
        J Immunother Cancer. 2022. doi: 10.1136/jitc-2022-004938. IF: 12.469
      • A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings

        Products & Services: vector cloning, adenovirus, AAV9
        Sci Adv. 2024. doi: 10.1126/sciadv.adq3374. IF: 11.7
      • Temporal variation in p38-mediated regulation of DUX4 in facioscapulohumeral muscular dystrophy

        Products & Services: vector cloning
        Sci Rep. 2024. doi: 10.1038/s41598-024-77911-8. IF: 3.8
      • Development and evaluation of vaccination strategies for addressing the continuous evolution SARS-CoV-2 based on recombinant trimeric protein technology: Potential for cross-neutralizing activity and broad coronavirus response

        Products & Services: stable cell line
        Heliyon. 2024. doi: 10.1016/j.heliyon.2024.e34492. IF: 3.4
      • Successful delivery of CRISPR-Cas9 with a baculovirus vector for insect brain targets

        Products & Services: vector cloning, CRISPR, baculovirus
        bioRxiv. 2024. doi: 10.1101/2024.11.26.624635.
      • Identification of a novel myosin antigen activating CD8+ T cells in C57BL/6 mice

        Products & Services: vector cloning
        bioRxiv. 2024. doi: 10.1101/2024.07.26.605251
      点击查看最新促銷活動信息
      HoME姐姐伦理电影_亚洲老妇性 劲爆欧美第一页_欧美无修正_韩国男女啪啪视频_欧美色毛视频v黄日韩一级毛片欧美一级下载看_路成黄网色aaa片不要vip的完整黄片_xingjao少女 欧美性爱看大片免费欧美色se seENTER NUMBET 0027yhhd-edu.com
      www.lngchinagas.com
      www.myd-china.com
      pcsoho.com
      onlinemanna.com
      www.twtoyschina.com
      aioverseasedu.com
      yuansoftware.com
      www.idugeni.com
      www.jieduyaon.com